We Manufacture of Palonosetron Hydrochloride API+Intermeidates CAS 135729-62-3

We Manufacture of Palonosetron Hydrochloride API+Intermeidates CAS 135729-62-3 with following detail:

Palonosetron Hydrochloride

Molecular formula ： C19H24N2OHCl

Molecular weight ： 332.87

CAS ： 135729-62-3

Application ：Antihypertension

Specification:

Product Palonosetron Hydrochloride

Reference standard Enterprise standard

Items Specification

Appearance White or whitish crystalline powder

PH: 4.0～6.0

Specific Optical Rotation: -100?～ -104?

Loss on Drying Not more than 1.0%

Residue on Ignition Not more than 0.1 %

Heavy Metals Not more than 20ppm

Sulphated Ash Not more than 0.02 %

Related Substances Not more than 1.0 %

Diastereoisomer Not more than 0.5 %

Assay Not less than 98.5 %

Palonosetron Isomer:

Palonosetron Hydrochloride(R. R) (R. S)(S. R)  Palonosetron Isomer

Palonosetron Intermediate
(S)-1,2,3,4-tetrahydro-1-naphthoic acid  85977-52-2 Palonosetron intermediate
5, 6, 7, 8-tetrahydro-1-naphthalenecarboxylic acid  4242-18-6 Palonosetron intermediate
(R)-1, 2, 3, 4-tetrahydro-naphthoic acid 23357-47-3 Palonosetron intermediate  
3-aminoquinuclidine dihydrochloride 6530-09-2 Palonosetron intermediate
(S)-(-)-3-aminoquinuclidine dihydrochloride  119904-90-4  Palonosetron intermediate
(R)-(+)-3-aminoquinuclidine dihydrochloride  123536-14-1  Palonosetron intermediate
N-(1-azabicyalo[2,2,2]oct-3S-yl)-1,2,3,4-tetrahydronaphthalen-1S-ylcarboxamine  Palonosetron intermediate

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